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The clinical recommendations address a common dilemma in perioperative care: whether patients on GLP-1 drugs should pause medication before surgery to reduce the risk of regurgitation and aspiration

Cochlear involvement in patients with systemic autoimmune rheumatic diseases: a clinical and laboratory comparative study

INTERCEPT Program of circulating tumor DNA (ctDNA) testing for minimal residual disease (MRD) in colorectal cancer (CRC)

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What they found: Melanotan II is 100 to 1000 more potent than native -MSH in melanocyte assays Cyclization preserves the active conformation longer than linear -MSH Activates all four functional melanocortin receptors (MC1R, MC3R, MC4R, MC5R) In vivo: visible pigmentation of lizard skin within hours, not days as with -MSH Why it matters: This is the foundational publication of Melanotan II

I didn't choose that because I didn't have so much access to small molecule chemists at the time, so I chose the fatty acid acetylation idea actually because I thought I can actually do that