You're reintroducing the peptide to an environment where it can fold, move, and, unfortunately, break down
DOI: 10.1016/j.bcp.2012.12.004
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
In a Phase I single ascending dose study in healthy participants, LY3437943 showed a similar safety and tolerability profile to that of other incretins and a reduction in body weight up to day 43 after a single dose [97]
Well-balanced meals with protein, fiber and healthy fats Meals that combine protein + fiber + fat result in stronger and longer-lasting GLP-1 secretion than carbs alone
Clinical Evidence Behind GLP-1 Therapy for Weight Loss The landmark STEP trials (Semaglutide Treatment Effect in People with obesity) demonstrated that patients on semaglutide lose 1522% of their starting body weight over 68 weeksfar exceeding results from diet and exercise alone