The peptide is fragilestomach acid and digestive enzymes destroy it before it can absorb
Tirzepatide is glucose-dependent in its mechanism, meaning it stimulates insulin secretion only when blood glucose is elevated
Having controlled glucose levels can help prevent severe complications from type 2 diabetes like kidney disease, retinal diseases, neuropathy (losing feeling in the hands and feet), and development of non-healing wounds in the feet, and experts are now looking into whether GLP-1s reduce the risk for those complications
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This review summarizes the existing knowledge derived from animal studies on the effects of GLP-1RAs and GLP-1RA related peptide polyagonists on NAFLD in an attempt to illuminate areas of uncertainty and provide the groundwork for future animal and clinical research in the field
