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Vina J, Perez C, Furukawa T, Palacin M, Vina JR

Health-conscious individuals concerned about metabolic health, those with family histories of diabetes or cardiovascular disease, and patients experiencing unexplained fatigue, weight changes, or vision problems should consider this screening (Epicentre 2025)

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[1] Inactivation of 2-OHE 2 is catalysed by catechol-O-methyltransferase (COMT), [2] with COMT exhibiting a faster rate for the methylation of 2-OHE 2 versus 4-OH-E 2

Ozempic may be an option for those individuals who are diabetic, have a body mass index (BMI) that is significantly over the healthy range (27 or above), have a weight-related disease, or have cardiovascular issues in addition to weight problems

Gentiopicroside, a secoiridoid glycoside from gentiana rigescens franch, extends the lifespan of yeast via inducing mitophagy and antioxidative stress