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By improving HRV, L-carnitine helps shift the autonomic nervous system out of chronic sympathetic overdrive (the "fight or flight" state) and enhances parasympathetic vagal tone (the "rest and digest" state), promoting a calmer, more regulated nervous system response to physical stressors

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Saviano A, Apta B, Tull S, Pezhman L, Fatima A, Sevim M

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Viral proteins as well as host damage-associated molecular patterns, that accumulate following cellular stress during viral infection, were linked to TLR4 activation, with uncontrolled TLR4 activation being associated with severe disease (Olejnik et al., 2018)