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The entire process is regulated by NF-kB, a master transcription factor that controls the expression of hundreds of inflammatory genes
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[45] The accumulation of neuronal and muscular ROS appears to contribute to age-associated impairments
PMID 15234992
Biochemistry 40:1413442, PMID: 11714266 Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, JanssenHeininger YM (2006) Dynamic redox control of NF-kappaB through glutaredoxin-regulated S -glutathionylation of inhibitory kappaB kinase beta
