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In fact, according to the NIH, its estimated that only about 5% of men and women ages 5170 take more than this amount per day, mostly due to the use of supplements ( summary Your body absorbs folic acid from fortified foods and supplements easier than it absorbs naturally occurring folate from foods

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Women with a history of breast cancer, blood clots, or stroke may not be candidates for this treatment, though transdermal and low-dose options are considered safer alternatives for some patients according to 2024 North American Menopause Society guidelines