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Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity

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Selenium deficiency can also interfere with converting T4 to T3, further reducing thyroid hormone activity

7 Clinical features of untreated Laron syndrome include severe post-natal growth failure (despite normal prenatal growth), short limb length (relative to trunk length), characteristic facial features (saddle nose and small forehead), delayed skeletal maturation and sexual development, small genitalia and testes, osteopenia, muscle weakness, obesity, and metabolic abnormalities (i.e., hyperlipidemia, hypoglycemia, and insulin resistance)

European Journal of Anaesthesiology, 18 , 419-422