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A phase 2, adaptive randomized, double-blind, placebo-controlled, multicenter, 52-week study of HM15211 in patients with biopsy-confirmed non-alcoholic steatohepatitis - Study design and rationale of HM-TRIA-201 study
doi: 10.1186/s13063-021-05442-y 161 ChenHLiuSGaoSShiHYanYXuYet al
The bridge steps are the consequence: skipping them is where the trouble concentrates
Over time, that pooling puts sustained pressure on the vein walls and surrounding tissue, producing the symptoms most people recognize: twisted, rope-like varicose veins, smaller spider veins, persistent leg swelling, aching, skin discoloration, and in advanced cases, open sores called venous ulcers
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