A pooled analysis of the STEP 1 through STEP 3 trials, published in Diabetes, Obesity and Metabolism in 2022, examined once-weekly semaglutide 2.4 mg in 2,117 participants against 1,262 on placebo
Flavonoids Flavonoids like quercetin, curcumin, and ECGC are GLP-1 boosters too
GI side effects A recent systematic review of 39 randomized controlled trials of GLP-1RAs showed a class effect of increased risks of nausea, vomiting, diarrhea and constipation compared with placebo (15) in individuals without diabetes
DV: Validation, Resources, Data curation, Methodology, Software, Writing original draft, Investigation
Transdermal patches solve both issues
While promising impressive outcomes regarding efficacy and health benefits beyond just losing weight, its crucial not to overlook possible adverse effects associated with Tirzepatide usage