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The extracts at 25 and 50 g/ml significantly increased ROI secretion and expression levels of IL-10 and IL-14, but the level of NO was decreased

Additionally, to verify the efficacy of CPP-CAND in triggering cancer cell senescence induced by other anticancer drugs, we tested its effects on senescent cancer cells induced by cisplatin (CDDP)

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Gradual Introduction: Start with lower concentrations (e.g., 0.05% to 1%) and less frequent application (e.g., every other day) to allow the skin to acclimate, especially for sensitive skin types

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