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Those impurities might include truncated peptide sequences, deletion variants missing one or more amino acids, oxidized forms of the peptide, or residual solvents from the synthesis process
J.CornerA.Yki-JarvinenH.EliassonB.et al
However, a significant decrease in insulinotropic activity was observed with GIP in diabetic patient with hyperglycemia, whereas relatively preserved activity was noted with GLP-1 in the same patients (58), suggesting divergent effects of GIP and GLP-1 on -cells ( Figure 1 Section B)
and Alonso, A
171 The development of small molecule GLP-1RAs aims to overcome some of the limitations of traditional protein or peptide-based GLP-1RAs, such as the need for injection
& Triggle, C
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