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Vagal receptors in the oropharyngeal area detect changes in taste and tension, activating the vagus nerve to initiate the vagovagal reflex of the stomach and facilitate the smooth entry of food into the stomach

Chronic oxidative stress reduces cellular GSH, and replenishment strategies are an active area of biochemical research

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Another imminent problem is that the GLP-1RAs that are currently used in the clinical setting are biological macromolecular peptide preparations, such as exenatide and liraglutide, with high production costs that limit their clinical application (231)

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