Kumar TR, Wiseman AL, Kala G, Kala SV, Matzuk MM, Lieberman MW: Reproductive defects in gamma-glutamyl transpeptidase-deficient mice
Higher levels of GLP-1 were found to disrupt mitochondrial function, leading to a significant decline in kinesin activity
Ex vivo glucose-stimulated insulin secretion from pancreatic islets Culture medium was removed and islet microtissues were equilibrated for 1 h with Krebs Ringer HEPES buffer (131 mM NaCl, 4.8 mM KCl, 1.3 mM CaCl 2 , 25 mM HEPES, 1.2 mM KH 2 PO 4 , 1.2 mM MgSO 4 and 2% BSA) containing 2.8 mM glucose
Injectable forms are preferred for GLP-1 users because they achieve higher bioavailability independent of digestive function
Rees TA, Tasma Z, Garelja ML, OCarroll SJ, Walker CS, Hay DL
There are the risks of venipuncture bleeding, bruising, clotting, and infection and you are going around the system evolutionary biology has so beautifully designed to be the conduit for nutrients to enter our bodies: the GI tract." So what's the bottom line on these treatments