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Preclinical and clinical trials should be designed accordingly, with a focus on conditions where antioxidant therapy is more likely to yield therapeutic benefit

If youre still unusually tired after a few weeks of consistent hydration and steadier eating, its worth checking other contributors (sleep, iron status, B12, vitamin D, thyroid) with your GP especially if you have dietary restrictions

But claims like cognitive supercharge lack strong clinical backing

On the calorie side, research has shown positive benefits from an energy surplus ranging from around 100 extra calories per day up to 1,000.32 The key is to evaluate your metabolism as closely as possible and adjust your caloric intake to slightly exceed the burn you get from your weight training

doi: 10.1007/s00125-011-2297-z

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