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To reduce noise, proteins with very low abundance were excluded by applying a median threshold of at least two PSMs

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Celecoxib We noted an immediate and then sustained effect on pressure in lower esophageal sphincter, and a postponed effect on pyloric sphincter after either 0.5 mg/kg or 1.0 mg/kg intraperitoneal challenge

Second, for data transformation, we applied a log transformation (base 10), which helps in stabilizing variance and normalizing data distribution, making the data more suitable for downstream analysis 82

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