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The researchers performed quantitative susceptibility mapping (QSM) iron deposition in the SN of 44 PD patients and 31 age- and sex-matched healthy controls and PD patients were found to exhibit significantly higher magnetic sensitivity values, especially in patients at advanced stage severity, confirming that iron accumulation in SN is consistent with PD progression (Moreau et al., 2018), and it might be a chance to cure PD in the future

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There are no large Western RCTs and no published phase 2/3 trials

Among them, TP53 exerts a context-dependent dual role in ferroptosis regulation 153

Gumus P, Emingil G, Ozturk VO, Belibasakis GN, Bostanci N