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However, if autophagy is impaired in the pancreatic acinar cells, it may not be able to take care of the intracellular damage leading to the inflammatory cascade.[ref] Additionally, autophagy is important in tamping down inflammation due to tissue damage

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Ketogenic diets are known to influence gut microbial composition and xenobiotic metabolism, and the observed decline may reflect changes in dietary exposure, microbial activity, or hepatic clearance

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