This architecture creates an extraordinarily high binding affinity (pK = 16.44), roughly 10 million times stronger than other tripeptides and comparable to albumins copper binding
Cell Probes 30 , 386396 (2016)
The -ketoacid dehydrogenase multienzyme complexes The -ketoacid dehydrogenase multienzyme complex family includes (1) the pyruvate dehydrogenase complex
In the LPS-induced acutelung injury mouse model, treatment of GHK-Cu also significantly suppressed TNF- and IL-6 expression with a significant decrease of both NF-B p65 and p38 MAPK signaling, suggesting that GHK-Cu is useful for the development of novel anti-inflammatory therapies [22]
It is GMO- free, hormone treatment-free, pesticide and chemical free and undergoes minimal processing
Pickart, credited with discovering GHK-CU: No issues (involving GHK-Cu) have ever arisen during its use as a skin cosmetic or in human wound healing studies [2]