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Most of this can be explained by the link between weight and risk described in Part 1, but mortality improvements observed in clinical trials that cannot be predicted from weight-loss alone are also allowed for

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GLP-1, or glucagon-like peptide-1, is a hormone that helps regulate blood sugar levels and appetite

Evaluation was performed in DiscoverMP (Refeyn Ltd) and molecular masses were determined by matching histogram contrast against a molecular weight standard (Invitrogen/Thermo NativeMark, LC0725)

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Studies have shown that variations in the GIPR gene are linked to cardiovascular disease and metabolic syndrome characteristics, which supports this idea [110]