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The study further shows that extended treatment duration elicits robust anti-fibrotic effects, consistent with the primary outcomes of the ESSENCE Phase 3 clinical trial, and recapitulates circulating biomarker signatures observed in semaglutide-treated MASH patients

Insulin sensitivity plays a role in weight change, with people who have poor sensitivity potentially benefiting more from drugs like tirzepatide, which can reduce HbA1c by as much as 2.4%

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[28] Coverage after the Bridge ends is currently undetermined

It can, especially early in treatment

Semaglutide Dosing: Can You Take Two Shots in a Week