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There are no clear published guidelines for management of skin pigmentation despite some clinical trials of shorter duration and small sample sizes

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Its deficiency, although rare, may present with dermatitis, brittle nails, and hair loss (248)

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[7] Androgen therapy can potentiate the hypoglycaemic effect of insulin and oral antidiabetic agents, necessitating closer monitoring of fasting glucose and possible dose reductions when testosterone replacement is initiated in diabetic patients