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CGRP, when released from the bodies or axonal swellings of stimulated trigeminal neurons, can trigger satellite glial cells within the trigeminal ganglia, as well as microglia and astrocytes in the trigeminal nucleus caudalis

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Similarly, maintenance of tissue oxygenation is highly dependent upon the balance between eryptosis and hematopoiesis [211]

FDA-approved branded options for the same indications are Wegovy and Ozempic (semaglutide, Novo Nordisk), Mounjaro and Zepbound (tirzepatide, Eli Lilly), and Rybelsus (oral semaglutide tablet, Novo Nordisk)

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