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Estimation of serum copper, superoxide dismutase and reduced glutathione levels in melasma: a case control study

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If methylation is sluggish (often for genetic reasons) or the body doesn't have enough nutrients (including vitamin B12 and folate) to turn the methylation cycle, the body can't make enough glutathione

doi: 10.1016/j.cgh.2009.07.017 108 MatsuokaKNishiumiSYoshidaMKodamaY

N-acetylcysteine (NAC) and its role in clinical practice management of cystic fibrosis (CF): a review