A medicina nas caravelas - Sculo XV Archived 4 September 2015 at the Wayback Machine Marujos, Alimentao e Higiene a Bordo "Scurvy During Magellan's Voyage"
Note that 2-PAM has an affinity for the acetylcholine anionic binding site on cholinesterase (right middle panel), which could explain the oxime related worsening of cholinergic side effects when 2-PAM is administered prior to the onset of action of atropine in the setting of organophosphate poisoning, by transiently preventing nerve-agent free cholinesterase from interacting with acetylcholine
10.1007/s00281-022-00910-2 76 UchiyamaM.MiharaM
Duems-Noriega O, Ario-Blasco S
Novo Nordisk has added ileus to the Postmarketing Experience section of the Wegovy label under Gastrointestinal Disorders. In October 2025, Severe Gastrointestinal Adverse Reactions was added to the WARNING AND PRECAUTIONS section of the label
Sexual Medicine, 4 (3), e166