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This discovery, more than any other, has led to the therapeutic translation of the basic science of incretin biology and the development of GLP-1 agonists resistant to degradation by DPP-4 and of selective inhibitors of DPP-4 activity as therapeutic agents

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Modica S, Straub LG, Balaz M, Sun W, Varga L, Stefanicka P, Profant M, Simon E, Neubauer H, Ukropcova B, Ukropec J, Wolfrum C

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