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Preclinical studies in animal models have demonstrated that survodutide effectively activates both GLP-1R and GCGR, resulting in reduced body weight, slower gastric emptying, decreased energy intake, increased energy expenditure, and improved glucose tolerance [86]

Prioritize Lean Proteins: Buy high-quality, lean proteins like chicken breast, Greek yogurt, or protein shakes

GLP-1, or Glucagon-like peptide-1 receptor agonists, are medications that treat type 2 diabetes and obesity

Although prior studies were performed using mice, a rationale exists for future studies examining TRPA1 channel-dependent regulation of GLP-1 secretion from human L-cells

H.et al (2002)

In general, GLP-1 is thought to have two effects, one exerted via the central nervous system and the other exerted via local receptors in the periphery