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Neuroprotective properties of GLP-1RAs observed in animal models of neurodegenerative diseases such as Alzheimers disease are very often associated with the reduction of inflammatory processes in the central nervous system

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63 Furthermore, BCAT 1 is selectively upregulated in isocitrate dehydrogenase (IDH) wild-type (WT) GBM, and -ketoglutarate (-KG) mediates cell death in BCAT 1-deficient IDH WT GBM

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