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While GLP-1s dont replace CPAP or BiPAP therapy, they meaningfully reduce apnea severity by driving weight loss

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In vivo , knockdown of LPCAT3 aggravates OA progression and inflammation, while pharmacological inhibition of ACSL4 partially rescues these effects (76)

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The first pathway requires a BMI greater than 27 combined with either prediabetes or established cardiovascular disease