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In clinical development programmes, dual agonism has been associated with substantial mean weight loss in selected populations when combined with lifestyle support

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The compound was never approved as a pharmaceutical treatment for obesity because the Phase 2 clinical trial results, while showing safety and modest efficacy, did not meet the threshold for drug registration

While GLP-1 analogs suppressed genes related to fatty acid synthesis, they had no significant effect on inflammation-related gene expressions

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By promptly addressing any concerns or issues that arise, your healthcare provider can help assure your health and safety throughout your weight loss journey