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Cardiovascular benefits of GLP-1 agonists in type 2 diabetes: a comparative review
1-4 PIONEER 3: In a double-blind, double-dummy trial with a primary endpoint of mean change in A1C from baseline to Week 26, 1864 adult patients with type 2 diabetes receiving metformin alone or metformin with a sulfonylurea were randomized to semaglutide tablets 14 mg (n=465), 7 mg (n=466), 3 mg (n=466), or Januvia 100 mg (n=467), all once daily
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This shift is expected to lead to increased medication costs, as compounded versions were often available at a fraction of the price of their branded counterparts