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Many patients with Long COVID and ME/CFS develop secondary Mast Cell Activation Syndrome (MCAS), leading to severe allergic-type reactions, hives, and gastrointestinal distress

Side effects are rare but may include mild irritation at the injection site, headaches, or temporary water retention

By inhibiting HDAC activity, these drugs aim to reverse the repressive effects of HDACs on gene expression and restore normal cellular function

PREVENTION *Break any habits of touching/rubbing/scratching the mouth or face with the hands

The ideal management strategy requires an organized systematic approach involving a coordinated team of dedicated diabetes care and education specialists (DCES) including nurse practitioners (NPs), the aim being to deliver patient-centered, individualized, high-quality care while empowering individuals with diabetes to actively participate in the management of their disease (

doi: 10.1007/s12020-021-02770-6 5 MuruganAKAlzahraniAS