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D-Nle-Cys-Ile-NH-(CH2) 5-CONH2 inhibits B16-F10 murine melanoma cell migration and lung colony formation Figure 29A illustrates the inhibitory response that was observed with daily intraperitoneal injections at two doses ( g/kg/day and 10( g/kg day) of [D-Nle-Cys-ne-NH-(CH 2 )5-CONH 2 ]

Both medications require titration , meaning people start on the lowest dose and gradually increase over time to minimize side effects

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The most frequently reported include nausea, vomiting, diarrhea, stomach pain, and decreased appetite

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