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Peptide combination rationale: AREDS2 provides antioxidants and macular pigment

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For people with normal B12, any weight change is usually small, inconsistent, and behaviorally driven (more activity, better appetite) rather than a direct effect of the vitamin

10.1016/j.neuron.2004.11.011 Neuron 213 ZhouY.WonJ.KarlssonM

For treating a deficiency, oral supplements are one approach, but intramuscular injection provides an optional, more direct channel

The clearest guidance comes from injection science more broadly