Sci Rep 8:1641 Hopkins FG (1925) Glutathione: its influence in the oxidation of fats and proteins
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100,101,102 A similar biphasic pattern occurs in MASLD: mitophagy is enhanced during early disease to counteract lipid excess and maintain mitochondrial homeostasis, but prolonged metabolic stress suppresses this adaptive response
This includes people who dont get enough sun, older people whose bodies are unable to produce as much Vitamin D, and people with darker complexions, whose skin is more resistant to the suns UV rays
doi: 10.1016/j.prp.2020.153247 175 YazdaniYMohammadnia-AfrouziMYousefiMAnvariEGhalamfarsaGHasanniaHet al
However, the role of ferroptosis in the progression of DKD remains controversial