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It has been proposed that astrocytes may induce the formation of the tight junctions between endothelial cells and influence the characteristic phenotype of the transporters of the blood-brain barrier (e.g., GLUT1 and amino acid transporter L1

They also work to regulate insulin, which can help reduce excess fat storage." Primary mechanisms: reduce hunger signals in the brain, increase early satiety, extend fullness duration between meals, slow gastric emptying

Agnelli G, Buller HR, Cohen A, et al

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The way Zepbound promotes weight loss is by increasing feelings of fullness, reducing hunger, and slowing down the rate at which food leaves the stomach