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What has not been established in human RCTs is whether these blood level increases translate to clinically meaningful outcomes in healthy people

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doi: 10.1017/S175173111700324X 4

G6pdh chon mice showed an upregulation of KEGG pathways for proteasome, protein processing in ER and ferroptosis, suggesting that G6PDH deletion affects proteostasis and lipid peroxidation, processes that can be linked to increased oxidative load

Further investigation could lead to new treatments for chronic conditions