A 1987 study on mice determined oral glutathione to be nontoxic,27 and a 2017 toxicity study (also on mice) found that glutathione's LD (the amount of a substance needed to kill 50% of all test animals in one dose) was 5g/kg.6 An equivalent toxic dose for an 80kg human would be 32.5g, which is more than 32 times the highest amounts used in clinical studies
Its also helpful for heavy metal overload, lyme, fibromyalgia, and chronic fatigue
Most people find that the benefits for skin, energy, and immune support become more noticeable after several weeks of consistent use.
To expound further on the previous question, most of these biomarkers are modulated by glutathione and its precursors at the mitochondrial level
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Sleep disorders are complicated, and many variables can ruin a good nights sleep