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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

, diabetes, dysbiosis), chemical reactivity enables spontaneous modification, potentiated by glyoxalase system dysregulation: methylglyoxal is converted by glyoxalase 1 (GLO1) to lactoylglutathione (LGSH), which undergoes non-enzymatic acyl transfer to lysine residues (55)

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ALCAR, thanks to its acetyl group, can cross the blood-brain barrier and additionally supports acetylcholine production, making it the preferred form for cognitive and brain-health goals