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These substances cant be targeted to a specific area and may instead activate pathways in tissues and systems that are actually detrimental to health, says Taylor

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This system has received considerable research attention related to its role in solid tumor cancers and possible therapies [72-74]

PMID 19699272

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Excess pigment can also be triggered by high levels of an amino acid known as homocysteine, which accumulates as a result of a B12 deficiency