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Oxidative Stress: A Culprit in the Progression of Diabetic Kidney Disease

However, evidence of the efficacy of enhanced control of glycemia in preventing neuropathy is stronger in patients with type 1 diabetes than in those with type 2 diabetes (73)

AUTHORS CONTRIBUTIONS All authors contributed greatly to the success of this work CONFLICT OF INTEREST No conflict of interest to declare in this manuscript ACKNOWLEDGEMENT This case was carried out without direct funding, and the authors would like to thank the Head and the entire staffs of the Department of Human Physiology, College of Medical Sciences, Ahmadu Bello University, Zaria, for their support and provision of necessary facilities

These compounds are identified as 4-hydroxyacetophenone (4-HAP), epicatechin-(4,8)-epicatechingallate (B2-3-O-gallate), red Sedum and p -tyrosol used mass spectrometry and nuclear magnetic resonance spectroscopy ( 2-[4-Alkoxy-3-(1H-tetrazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic Acid Derivatives The researchers in this study designed and synthesized a series of 2-[4-alkoxy-3-(1H-tetrazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives (8a-8z) and further evaluated their inhibitory effect on xanthine oxidase in vitro (Zhang et al., 2019)

Makino A, Skeleton MM, Zou A, Cowley AW

doi:10.1016/j.neuroscience.2009.08.026 78