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In the PIPD dataset, additional clinical assessments included the MMSE for cognitive function, the HAMD for depressive symptoms and the HAMA for anxiety symptoms

Fatigue is also common, which can make it harder to continue with gentle exercise or light physical activity

Pregnancy, breastfeeding, and minors: excluded there is no safety data in these groups

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Of note, ChAT neurons at all segments were frequently contacted by GLP-1R axon varicosities (Supplementary Fig