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Supplementary material The Supplementary Material for this article can be found online at: References 1 Al-SabahS

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One camp seems really bullish on this

The selectivity of the peptide is further discussed by the researchers, who suggest that senescent cells may depend more strongly on FOXO4-mediated control of p53 localization and activity, so disrupting that node might preferentially remove cells that are already operating close to an apoptotic threshold

This shift does not diminish the importance of safety, but it underscores the need to evaluate peptide systems within an appropriate therapeutic context rather than through overly conservative early-stage filters

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