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Sudden large increases in fiber can cause bloating and gas, especially when combined with Retatrutides effects on gut motility

o Constipation: Some individuals experience constipation instead of diarrhea

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At 24 weeks, mean percentage decrease in weight (primary outcome) ranged from 7.2% to 17.5% with different retatrutide doses compared with 1.6% with placebo

This mechanism is likely crucial for mediating liraglutide-induced weight loss (Secher et al 2014)

How do you stay on the drug at a level that won't cause weight loss, but does actually convey these cardiorenal benefits