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Nine different substances were declared or identified as undeclared PCT drugs in the samples and, in order of occurrence frequency, they were clomiphene, hCG, tamoxifen, exemestane, anastrozole, cabergoline, letrozole, mesterolone, and raloxifene (Figure 9)

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Additionally, within the testosterone-stimulated granulosa cells, we validated the expression of key genes, confirmed senescence and sphingolipids dysregulation, and evaluated the therapeutic efficacy of the candidate agent