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SGLT2 inhibitors may improve metabolic profiles in selected non-pregnant patients, but any such use must remain strictly outside pregnancy, under reliable contraception, and with guideline-consistent discontinuation before conception attempts because of urogenital adverse effects and contraindications during pregnancy (155, 156)

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Metagenomic and transcriptomic analyses reveal the differences and associations between the gut microbiome and muscular genes in Angus and Chinese Simmental cattle

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