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10.1074/jbc.M111.310342 [DOI] [PMC free article] [PubMed] [Google Scholar] Clift, D

The goal is not to race to the top dose, but to stay at the lowest dose that provides benefits without side effects, using a responsive microdosing protocol: Start at the lowest measurable dose

Bibliography Sources Exercise training attenuates MuRF-1 expression in the skeletal muscle of patients with chronic heart failure independent of age: the randomized Leipzig Exercise Intervention in Chronic Heart Failure and Aging catabolism study.Gielen S1, Sandri M, Kozarez I, Kratzsch J, Teupser D, Thiery J, Erbs S, Mangner N, Lenk K, Hambrecht R, Schuler G, Adams V

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In cirrhotic patients, nociceptive pain arises from various sources such as pathological fractures, ascites, splenomegaly, muscle cramps, musculoskeletal diseases like avascular necrosis and septic arthritis, and mastalgia (67, 68, 82)