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Briefly, the GLP-1R reporter cells were seeded into white-bottom 96-well assay plates in cell recovery medium (200 L/well) and incubated at 37 C in a humidified atmosphere of 5% CO 2 for 5 h

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Published mechanisms include upregulation of growth hormone receptor expression, promotion of angiogenesis via VEGF pathway activation, modulation of the nitric oxide system, and interaction with the dopaminergic and serotonergic systems in neurological models

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