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Dopamine -hydroxylase is a major vitamin C and copper (Cu 2+ )-dependent enzyme whose activity is negatively affected in Menkes disease

On the other hand, glutathione, a still relatively under-the-radar antioxidant, does occur naturally in the body

People with naturally brighter or "glowing" complexions often have a higher ratio of pheomelanin

periportal hepatocytes may contain nearly twice the centrilobular concentration, enterocytes at the villus tip have a higher content than the crypts, and renal proximal tubular cells have more GSH than other parts of the nephron (56)

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Conversely, GGCT overexpression elevated TCA cycle intermediates (Fig