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Epithalon and Epitalon are two spellings for the same peptide
Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH
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Interestingly, in the pooled analysis of OPERA I/II RCTs, the proportion of patients with 12-week CDI, defined as an EDSS decrease confirmed at 12 weeks, was higher with ocrelizumab compared with IFN -1a, although this was significant in the OPERA I (20.0% vs 12.4%, 61% difference, p = 0.01) but not in the OPERA II (21.4% vs 18.8%, 14% difference, p = 0.40) [2]
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